The adoption of healthy eating prevents imbalances in our intestinal microbiome, thus preventing the development of insulin resistance.
The inability to correctly use insulin - or what is the same, to develop ‘insulin resistance’ - could be avoided simply with healthy eating.
And it is that as it shows a study led by researchers from the University of Copenhagen (Denmark), the composition of our intestinal flora, which can be regulated with the diet, is responsible for the end of suffering or not this type of resistance and, therefore,, type 2 diabetes.
As explained by Oluf Pedersen, director of this research published in the "Nature" magazine, "our results show that certain specific imbalances in the intestinal microbiome contribute essentially to insulin resistance, a precursor state of generalized disorders such as diabetes type diabetes2, arterial hypertension and atherosclerosis, epidemic diseases whose prevalence continues to grow ».
question of bacteria
To carry out the research, the authors had the participation of 75 patients diagnosed with type 2 diabetes and 277 'healthy' –ujetos control - in which they analyzed the blood levels of more than 1,200 metabolites and made a thoroughgenetic analysis of more than a hundred bacteria residing in the intestinal tract.
The results showed that people with insulin resistance had high blood concentrations of an amino acid subtype called ‘branched chain amino acids’ (BCAA).And also, and what is more important, that this elevation of the BCAA is mediated by the changes in the composition and function of the intestinal flora.
Some specific imbalances in the intestinal flora contribute to insulinoluf pedersen resistance
Specifically, the bacterial species ‘Prevotella Copri’ and ‘Bacteroides vulgatus’, regular residents in our intestinal microbioma, are responsible for the biosynthesis of these BCAA.
So, can these bacteria be expected to be also involved in the development of insulin resistance?Well, to evaluate this possible relationship, the researchers conducted a study with an animal model - oratones - to which they fed with large amounts of ‘P.Copri ’over three weeks.
And what happened?Well, mice saturated with the bacteria, in addition to showing unusual highly high blood BAA levels, developed insulin resistance and glucose intolerance.
As Henrik Bjorn Nielsen, co-author of the investigation, indicates, in which the serum metobolomics, the microbiota and the clinical data in a single analysis are combined for the first time, represents a very significant advance at the level of both technical anddoctor.And what is most remarkable, the analysis describes the importance of the different bacterial species in relation to the disease, thus allowing us to identify a bacterium that causes insulin resistance when transferred to an animal model ».
you have to eat well
In short, the composition of our intestinal flora conditions our risk of insulin resistance and, therefore, of type 2 diabetes development. But to avoid suffering this resistance we just have to adopt a very simple measure: take care of our diet.
As Oluf Pedersen concludes, «most people with insulin resistance do not know that they suffer.However, it is well known that most overweight and obesity individuals have insulin resistance.And in the same way, that low -calorie diets, rich in vegetables and with a low content ofAnimal fats tend to normalize imbalances in intestinal flora and, simultaneously, improve insulin sensitivity.
Source: ABC.es
