Clinical trials will begin in a year.
The type 1 form of diabetes affects between 20 and 40 million people worldwide.It is a decrease in the ability to produce insulin (used by body cells to absorb blood glucose) as a result of the destruction of beta cells of the pancreatic tissue caused by the body's own immune system, often duringThe first years of life (it should not be confused with the most prevalent variety, of type 2, which tends to affect individuals in adulthood).Now, a vaccine prototype that could prevent this disease in children will begin clinical trials in 2018.
More than 20 years of research, according to an article published in Vaccine, have provided solid evidence of the link between the Coxsackievirus B1 enterovirus and the autoimmune reaction that makes the body destroy the cells in their own pancreas.It is not a cure, and will not eliminate the disease completely, but the vaccine is expected, created by researchers from the University of Tampere (Finland), provide immunity against virus and potentially reduce the number of new diabetes cases every year.
Enterovirus are responsible for polio, aposta fever, meningitis and myocarditis.There has been suspicion of a link between this group of pathogens and diabetes for several years.They are surprisingly common in newborns, and American disease control and prevention centers (CDC) have discovered that around a quarter of the 444 infections by enterovirus known in the United States in 2007 were caused by Coxsackievirus B1 (CVB1).In 2014, the team conducted a couple of studies in Finnish children with type 1 diabetes to demonstrate that, at least one of the six viruses in group B of Coxsackievirus, was associated with the condition.
If everything goes well, this new vaccine could end that and also help reduce other infections by enterovirus.The preclinical essays are just the first step.The next phase will include testing in healthy adult human beings.Of course, until you see the first satisfactory results, eight years could happen, "so we should not expect anything revolutionary too soon," says the researchers.
Meanwhile, the American Research Foundation of Juvenile Diabetes (JDRF) continue to finance research to find better ways to prevent and treat type 1 diabetes improving the technology that mimics the function of the pancreas or identifying ways of regenerating the producing cellsof insulin.
According to the World Health Organization, 422 million adults worldwide have diabetes, bad that causes at least one and a half million deaths every year.For their part, last month, scripps researchers Whittier Diabetes Institute published a study in the magazine Diabetes Care that realizes that low -income Hispanics with type 2 diabetes who received text messages about their health, daily and for six monthsThey saw improvements in their blood sugar levels similar to those caused by some glucose reducing medications.This is the first random controlled study to examine the use of text messages to attend Hispanic patients, without optimal access to health services, to control their diabetes.
