Consultation: High anti insulin and celiachy and hypothyroidism antibodies

what you feel during the exam

When the needle is introduced to extract the blood, some people feel moderate pain;Others only feel a puncture or feeling of bite.Subsequently, there may be some pulsatile sensation or a mild hematoma, which soon disappear.

reasons why the exam is carried out

This exam can be done if:

- It has or is at risk of type 1 diabetes
- It would seem to have an allergic reaction to insulin
- Insulin no longer seems to control your diabetes

Normal results : Normally, there are no antibodies against insulin in your blood.

The ranges of normal values ​​may vary slightly between different laboratories.Some laboratories use different measurements or analyze different samples.Talk to your medical care provider about the meaning of the specific results of your exam.

Meaning of abnormal results

If you have IgG and IGM antibodies against insulin, your body reacts to it as if it were something strange.This occurs because the antibody prevents insulin from working properly in cells.Consequently, blood sugar can be unusually high.

Antibodies can also prolong the effect of insulin by releasing something from it long after food has been absorbed.This can be at risk of hypoglycemia.

If the exam shows high levels of the IGE antibody against insulin, your body has developed an allergic response to insulin.This could put it at risk of severe skin reactions where insulin injects.It can also develop more serious reactions that affect blood pressure or breathing.

Other medications, such as antihistamines or injectable steroids in low doses, can help decrease reaction.In the event that the reactions have been serious, a treatment process called desensitization may be required.

risks
The veins and arteries vary in the size of a patient and another and from one side of the body to another, which is why obtaining a blood sample of some people can be more difficult than others.

Other risks of blood extraction are slight, but may include:

- Excessive bleeding
- Fainting or feeling of dizziness
- Hematoma (accumulation of blood under the skin)
- Infection (a slight risk every time the skin break is presented)
- Alternative names
- Antibodies against insulin - serum;Exam for anti -sulin antibodies;Insulin resistance - insulin antibodies;Diabetes - Antibodies against insulin

References
Atkinson Ma.Type 1 diabetes mellitus.In: Melmed S, Polonsky Ks, Larsen PR, Kronenberg HM, eds.Williams Textbook of Endocrinology.13th ed.Philadelphia, Pa: Elsevier;2016: Chap 32.

Hamilton RG.Laboratory Tests for Allergic and Immunodeficiency Deseodas.In: Adkinson NF JR, Bochner Bs, Burks AW, et al, eds.Middleton's Allergy: Principles and Practice.8th ed.Philadelphia, Pa: Elsevier Saunders;2013: Chap 74.

LAST REVIEW 2/3/2016
English version reviewed by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Amp;Nutrition, University of Washington School of Medicine, Seattle,Wa.Also Reviewed by David Zieve, MD, MHA, OGILVIE ISLAND, PHD, AND THE A.D.A.M.Editorial Team.

Translation and location carried out by: Drtango, Inc.