This is shown by a study by scientists from the Erasmus University of Rotterdam, in the Netherlands.
Erasmus University scientists in Rotterdam (Netherlands) have seen that women who have early menopause, before the age of 40, have a greater risk of developing type 2 diabetes compared to those who develop it more late.
This follows from the results published in the Diabetologia magazine, of the European Association for the Study of Diabetes, which add to those of a work previously carried out by the same researchers who have already linked early menopause to a greater risk of cardiovascular diseaseand mortality for any cause.
adverse effects
Although it is thought that the increase in risk is due to the adverse effects of menopause on cardiovascular risk factors, the influence of age on menopause on these risk factors is still uncertain.
The authors used data from a prospective study in the Ommoord district of Rotterdam, which included a total of 3,969 women over 45 years after leaving out those who already had type 2 diabetes, had not reached menopause or had done it but had done it butIn an unnatural way.
The menopausal state was evaluated by a home questionnaire with which, among other measures, the age at which they had had the last menstrual period was completed.During the subsequent periodic follow -ups, every 3 to 5 years, the prevalence of type 2 diabetes was evaluated from the different medical reports, hospital income or blood glucose levels.
Of the 3,639 women without diabetes at the beginning of the study, 348 developed the disease after a median follow -up of 9.2 years.And compared to women who had late menopause (55 years or later), those who had a menopause before the age of 40 were almost 4 times more likely to have diabetes.And if they were between 40 and 44 years, 2.4 times more likely.
reduction
In general, the risk of developing type 2 diabetes was reduced by 4 percent for each year that took a woman to develop the symptoms of menopause.In addition, the adjustment of various factors that could influence did not affect this risk.
The authors suggest that "future studies must explore epigenetic brands related to the beginning of menopause to see if they can also explain this association.
"The early beginning of menopause is an independent marker for type 2 diabetes, but more studies are needed to examine the mechanisms that underlie this association and explore whether the age of natural menopause has no value in the prediction and prevention of theAdded diabetes, "they have insisted.
