A large -scale study of dietary treatment in type 1 diabetes

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The Dietary Science Foundation has allocated 60,000 EUR to researchers at the Karolinska University Hospital to study how diets with various amounts of carbohydrates affect blood sugar control in type 1 diabetes. One in four people with diabetes type diabetes1 has serious problems with blood sugar control, so best dietary treatments can save lives.

About 50,000 children and adults in Sweden have type 1 diabetes and the disease is increasing in many countries.Despite the large number of patients, it is not clear what dietary advice are more effective in counteracting long -term complications, such as kidneys, eyes and cardiovascular diseases.The Swedish National Board of Health and Welfare writes on its current advice on food for diabetes: "The best diabetes diet is a subject of intense debate. The area is partially unexplored and scientific evidence is weak."

"Doctors in diabetes like me have no solid scientific evidence on which to base good advice. Therefore, patients can receive different recommendations according to the doctor with whom they are, and that creates confusion. In their place, many people seekInternet information.

To fill this knowledge void, the Dietary Science Foundation will support a clinical trial directed by Anneli Björklund, associate teacher and chief doctor, in the Endocrinology, Metabolism and Diabetes Unit of the Karolinska Hospital.She sees a great need for better science in the area:

"It is important that patients receive dietary advice that helps them feel as healthy as possible. As attending doctors we receive many questions about food, but we do not have solid scientific evidence to support the advice we give," he says.

In the study, which will be one of the largest dietary studies for people with type 1 diabetes, 150 adults with blood sugar control problems will be randomly assigned in three different groups.It will be recommended to a group that follows a traditional diabetic diet (50-60% carbohydrates), a second group will follow a moderate diet low in carbohydrates (30-40% carbohydrates) and a third group will follow a strict low diet in carbohydrates.(10-20% carbohydrates).

During the first months of the study, patients will receive intensive support while they follow dietary treatment, and the effects of diet change will be studied for a year.

“If patients lower their blood sugar, their risk of long -term complications will eventually be reduced.We must also ensure that dietary treatments do not cause any dangerous side effect.So, among other things, we will monitor the frequency with which patients suffer from hypoglycemia and ketoacidosis.We will also follow their blood lipid levels, "says Anneli Björklund.

There is an ongoing debate about the risks of a low carbohydrates diet in type 1 diabetes. On the one hand, eating foods with low carbohydrate content increases the risk of hypoglycemia (a blood sugar level too low) and ketoacidosis (a potentially deadly condition in which blood becomes acidic).The other side maintains that a low carbohydrate diet leads to sugar levels inthe most stable and, therefore, at a lower risk of both hypoglycemia and ketoacidosis.

“The debate has been quite ugly.We believe it is important to do a scientific study well designed to discover how things are, "says Kerstin Brístar.

He is well raised and has already given him the ethical approval so they can begin.Let's see when you publish the results which are the conclusions.

How can a low carbohydrate diet cause ketoacidosis?I understand hypoglycemia, but ketoacedosis is only with hyper ..

xelbun said:
How can a low carbohydrate diet cause ketoacidosis?I understand hypoglycemia, but ketoacedosis is only with hyper ..

When you get a lot of hydrates, you enter a normal metabolic state called "ketosis."That is simply that your body uses fat as energy and produces ketone bodies that use some organs such as energy (for example the brain can obtain much of the energy of the ketone bodies), and the little glucose you need can produce the liver.That in a very summary way.
Many people do not distinguish between nutritional ketosis and ketoacidosis and hence believing that when you lower hydrates you can have ketoacidosis.As your good say ketoacidosis is caused by hyperglycemia, really due to lack of insulin that causes hyperglycemia, dehydration (the body tries to expel glucose through urine) and also increases the production of ketone bodies in a uncontrolled way.If there is no lack of insulin, the body maintains the ketonic bodies within normal levels that are not any problem.If there is a lack of insulin, the thing is already out of control.The risk of ketoacidosis is really the same comas what you eat because problem comes due to the lack of insulin that causes hyperglycemia maintained.A specific glucose peak is not any problem even if you make a very low food in hydrates, the problem would come if you forget to put the insulin or in the case of pump users the infusion is blocked.But that would also happen independently of food.But it is an argument against this type of food that they usually use due to ignorance of how all this works.
Nor does the risk of hypoglycemia increase whenever insulin adjusts.Hypoglycemia is just otherwise, too much insulin.If the dose is adjusted to food there is no hypoglycemia.Then in practice we all know that it is not so easy and there are always dose calculation errors that cause hypoglycemia, but when using very small amounts of fast insulin, errors are usually much smaller and the softest hypoglycemia.
I follow this type of food and my hypoglycemia are usually due to the calculation of fast but quite soft and are quickly fixed with a little glucose.I use pure glucose and many times I only need half a pill (2.5gr) to overcome or avoid hypo.