Effectiveness of the monoclonal antibody in diabetes

According to the latest research, monoclonal antibodies could be effective in the treatment of type 1 diabetes. Although at the moment it only applies in the early phases of the disease, specialists are optimistic and trust in achieving, in the future, a treatmentNo need to administer insulin.

Monoclonal antibodies have already shown plenty of effectiveness in the treatment of different types of tumors and even in the management of some allergies.Now it has touched the diabetes turn that you already see in these treatments a possible alternative to the administration of insulin."The latest investigations are demonstrating that the use of monoclonal antibodies is revealed effective in slowing the pancreatic destruction caused by the pathology; the beta cells of the pancreas are preserved in greater numbers and for longer, so that insulin production byPart of the patient is maintained, "said Luis Castaño, a researcher at the University of the Basque Country, during the 50th Congress of the Spanish Society of Endocrinology and Nutrition (SEEN).Although the results are positive, this treatment is only administered, for the moment, in patients who are in the disease debut phase.However, Castaño does not rule out "that a treatment for type 1 diabetes is achieved without insulin."

On the other hand, the treatment and diagnosis of type 2 diabetes already has a new guide that was presented during Congress.According to Alfredo Yoldí, a member of the working group that developed the document, one of the most important aspects is "the reinforcement of preventive treatment through diet and physical exercise to avoid overweight, one of the main causes of diabetes appearance"Similarly, this specialist highlights the need to carry out an early screening of microvascular complications to detect the appearance of the disease in the early stages.

The new data confirms relationship between the iodine deficit during pregnancy and the brain development of the baby."It has been observed that the children of mothers who had inadvertent hypothyroidism during pregnancy, have a lower intellectual quotient," said Manel Puig, vice president of the SEEN."We also have evidence that low thyroxine values ​​in the mother are associated with a higher frequency of ADHD. That is why we must ensure that the reserve of pregnant women is sufficient," he said.

Redifferentiation in thyroid cancer could be effective in the most aggressive neoplasms

90 percent of thyroid cancers heals with the first therapeutic performance, that is, complete exeresis surgery of the thyroid gland and radio -iodine administration or radioactive iodine.However, the objective for specialists is to find solutions for 10 percent of cases in which the radio is not effective."Thyroid cancer cells retain iodine pumps that normal thyroid cellCornerstone of treatment, it is no longer effective, "said Manel Puig, of the Endocrinology Service of the Clinic Hospital of Barcelona and Vice President of the SEEN, during the 50th Congress of the Society.In this sense, the lines of research that are being developed are aimed at reversing this situation through the redifferentiation, a process by which these cells again express the iodine pumps and, therefore, they are again susceptible to the treatment with radiiodine."Some compounds that are already used for other pathologies can be administered in these cases through compassionate use.Cases in which thyroid cancer causes pulmonary lesions and cells do not capture radiiodine, a retinoic acidic therapy achieves radio recapture in 30 or 35 percent of cases. "In this sense, tests are already being developedClinicians aimed at which percentage of patients could achieve iodine reuptake through redifferentiation with retinoic acid.

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