Scientists from Maynooth University (Ireland) have identified a protein in the body, called 'Pellino3', which can have the potential to prevent the development of obesity induced diabetes, thanks to the fact that it could block the inflammation produced by this disease and, therefore, avoid insulin resistance and diabetes.
According to the research, led by Professor Paul Moynagh, there is a direct correlation between the levels 'Pellino3' and the abdominal levels fatty tissue in individuals.In fact, in the study, the presence of the 'Pellino3' protein was extremely low among obese people, compared to thin people.
The lowest levels of 'Pellino3' are associated with the production of a critically important proinflammatory protein called IL-1 that leads to inflammation diabetes."After almost three years of research we have identified a new regulation mechanism to control diabetes induced by the diet, highlighting a key role of 'Pellino3' in the regulation of inflammation," Moynagh explained.
The research project has been funded by the Scientific Foundation of Ireland (SFI) with the support of experts from the San Vicente Hospital, Dublin.The conclusions of the research have been published in December in the magazine 'Scientific Immunity'.
